Cystic fibrosis

Cystic fibrosis (CF) is a life-threatening, inherited disease that can cause severe lung damage and complications associated with poor nutrition.  Brought about by a genetic mutation, cystic fibrosis affects secretory cells. In healthy individuals the secretions of these cells are thin and slippery and act as lubricants. In people with cystic fibrosis the secretions become thick and viscous and clog up the secretory passageways. This occurs most significantly in the pancreas and lungs. In the lungs, cystic fibrosis can lead to respiratory failure which can be life-threatening. In the pancreas, enzymes for the digestion of proteins and fats can not be properly secreted which then prevents the body from obtaining the nutrients and materials it needs.